Sacagawea, age 16 and pregnant, joins Lewis & Clark expedition as translator and guide.
Catherine Brewer became the first woman to receive a bachelor’s degree in the United States from Georgia Women’s College which is now Wesleyan College.
Women from textile mills in Lowell, Massachusetts formed the Lowell Female Labor Reform Association (LFLRA). The organization led by Sarah Bagley, testified before the Massachusetts legislature that new requirements forcing them to tend more machines at accelerated rates were damaging their physical well-being.
First Women’s Rights Convention held in Seneca Falls NY.
Elizabeth Blackwell, first female Medical Doctor in US.

Newly freed black women, working as laundresses in Jackson Mississippi, formed a union strike for higher wages
Equal Pay for Equal Work presented by National Labor Union.
Women shoe stitchers from six states form the first national women’s labor organization, the Daughters of St. Crispin.
First women’s suffrage law passed in WY.
Different views on racial equality for Black women split National Women Suffrage Association and American Women Suffrage.
Victoria Claflin Woodhull is the first woman to run as a presidential candidate.
Supreme Court denies women right to vote.
Belva Ann Lockwood becomes the first woman lawyer to practice before the U.S. Supreme Court.
Lucy Parsons along with her husband Albert Parsons found the International Working Peoples Association (IWPA).
The Knights of Labor, the first large scale national labor union admits women. Leonora O’Reilly, a member of the Knights of Labor, organizes a female chapter naming it United Garment Workers of America (UGWA).
The National Consumer League, founded and sought to improve working conditions for women.
